李涛

医疗特长(限400字内)：

生殖医学实验室操作与管理

研究方向：

生殖医学，人配子体外受精，人类胚胎体外培养，配子及胚胎冷冻保存

主要教育和工作经历：

2003年至今中山大学附属第一医院生殖医学中心，胚胎实验室工作;

2000年-2003年中山大学附属第一医院生殖中心生殖医学专业，获医学博士学位;

1997年-2000年中山医科大学基础医学院组织胚胎学专业，获得医学硕士学位;

社会兼职：无

论著：

1. LiT, Zhou CQ, Mai QY, Zhuang GL. Establishment of human embryonic stemcell line from gamete donors. Chin Med J (Engl). 2005 Jan20;118(2):116-22.

2. LiT, Zhou C, Liu C, Mai Q, Zhuang G. Bulk vitrification of human embryonicstem cells. Hum Reprod. 2008 Feb;23(2):358-64. Epub 2007 Dec 14.

3. LiT, Mai Q, Gao J, Zhou C. Cryopreservation of human embryonicstem cells with a new bulk vitrification method. Biol Reprod. 2010May;82(5):848-53. doi: 10.1095/biolreprod.109.080713. Epub 2010 Jan 14.

4. HuangJ, Li T, Ding CH, Brosens J, Zhou CQ, Wang HH, Xu YW. Insufficienthistone-3 lysine-9 deacetylation in human oocytes matured in vitro isassociated with aberrant meiosis. Fertil Steril. 2012 Jan;97(1):178-84.e3. doi:10.1016/j.fertnstert.2011.10.023. Epub 2011 Nov 17

5. Bian J,Li T, Ding C, Xin W, Zhu B, Zhou C. Vitreous Cryopreservation of HumanPreantral Follicles Encapsulated in Alginate Beads with Mini Mesh Cups.J Reprod Dev. 2013 Mar 14. [Epub ahead of print] 共同第一作者

6. Khoudja R, Li T,Ding C, Xu Y, Liu Y, Zhou W, Zhou C. Effect of co-incubation of oocyteswith a decreasing number of spermatozoa on embryo quality. Reprod Biomed Online. 2013 Apr;26(4):353-9. doi:10.1016/j.rbmo.2012.12.009. Epub2012 Dec 28. 共同第一作者

7. Fang C,Li T,Miao BY,Zhuang GL,Zhou C.Mechanically expanding the zona pellucida of human frozen thawed embryos: a newmethod of assisted hatching. Fertil Steril. 2010 Sep;94(4):1302-7. doi:10.1016/j.fertnstert.2009.08.014. Epub 2009 Sep 26.共同第一作者

8. Fang C, Tang M, Li T, Peng WL, Zhou CQ, Zhuang GL, Leong M. Visualization of meiotic spindle andsubsequent embryonic development in in vitro and in vivo matured human oocytes.J Assist Reprod Genet. 2007 Nov;24(11):547-51. Epub2007 Sep 27.

9. Khoudja RY, Xu Y, Li T, Zhou C. Better IVF outcomes followingimprovements in laboratory air quality. J AssistReprod Genet. 2013 Jan;30(1):69-76. doi: 10.1007/s10815-012-9900-1. Epub2012 Dec 16.

10. Zhou CQ, Mai QY, Li T, Zhuang GL. Cryopreservation of human embryonicstem cells by vitrification. Chin Med J (Engl). 2004Jul;117(7):1050-5.

11. MaiX, Mai Q, Li T, Zhou C. Dynamicexpression patterns of imprinted genes in human embryonic stem cells followingprolonged passaging and differentiation. J Assist Reprod Genet. 2011Apr;28(4):315-23. doi: 10.1007/s10815-010-9524-2. Epub 2010 Dec 16. PubMedPMID: 21161363; PubMed Central PMCID: PMC3114963.

12. WangH, Zhou C, Chen W, Li T, Huang J,Zhuang G. Supraphysiological estrogen levels adversely impact proliferation andhistone modification in human embryonic stem cells: possible implications forcontrolled ovarian hyperstimulation assisted pregnancy. Eur J Obstet GynecolReprod Biol. 2011 Mar;155(1):58-64. doi: 10.1016/j.ejogrb.2010.11.014. Epub2010 Dec 21. PubMed PMID: 21177016.

13. XingW, Zhou C, Bian J, Montag M, Xu Y, Li Y, LiT. Solid-surface vitrification is an appropriate and convenient method forcryopreservation of isolated rat follicles. Reprod Biol Endocrinol. 2010 May11;8:42. doi: 10.1186/1477-7827-8-42. PubMed PMID: 20459796; PubMed CentralPMCID: PMC2887875.

14. MaiQ, Yu Y, Li T, Wang L, Chen MJ,Huang SZ, Zhou C, Zhou Q. Derivation of human embryonic stem cell lines fromparthenogenetic blastocysts. Cell Res. 2007 Dec;17(12):1008-19. PubMed PMID:18071366.