李涛

李涛，女，博士，研究员，精神病学博士生导师。国家杰出青年科学基金获得者。 1987毕业于华西医科大学，获医学学士学位，同年留华西医科大学附一院工作，任住院医师。1994年获华西医科大学精神科博士学位，毕业后任华西医科大学附一院精神科主治医师1995-1996年赴英国伦敦大学精神病研究所遗传研究室作为访问学者开展国际合作研究，1997年再次赴英国伦敦大学精神病研究所遗传研究室进行博士后研究工作，1998年至今任英国伦敦大学精神病研究所遗传研究室讲师。1998-2000年任四川大学华西医院精神科副研究员，2000年晋升为研究员，现任四川大学华西医院心理卫生中心主任和精神医学研究室主任、博士生导师，拥有临床精神病学(中国)和遗传学(英国)双博士学位。多年来潜心致力于精神疾病的病因学研究，特别是在探索精神分裂症的分子遗传机制方面取得了一些重要的研究成果，如在国际上率先报导COMT基因与精神分裂症的发病相关。近几年来开展了大量以精神分裂症为代表的精神疾病遗传生物表型和分子遗传的研究工作,从大脑结构、功能和生化代谢等角度全面探讨高级认知活动的神经生物学基础及其与精神疾病的关系，系统分析基因与疾病及其生物遗传标记的关系。李涛教授作为项目负责人先后承担了20多项国家级和国际科研项目，共发表SCI引用论文70余篇。先后于1997年获中国卫生部颁发的“吴阶平医学研究奖和保罗.杨森药学研究奖精神病学专业三等奖”、2001年获中共中央组织部、人事部、中国科学技术协会联合颁发的第七届“中国杰出青年科学家奖”、2002年获国家自然基金委享有盛誉的“国家杰出青年科学基金”、2005年获中华全国妇女联合会、中国科学技术协会、中国联合国教科文组织全国委员会、欧莱雅中国联合颁发的第二届“中国女青年科学家奖”、 2006年入选四川省人民政府“四川省学术和技术带头人”、2008年获教育部自然科学一等奖(排名第一)、2008年获教育部创新团队(带头人)及2009年获教育部长江学者特聘教授称号。

【任职】

中国神经科学学会精神病学临床与基础专委会常委，中华医学会精神病学分会委员;中华医学遗传学杂志编委，四川大学学报(医学版)编委

【研究方向】

精神疾病的生物学机制研究

现任职务:

精神医学实验室主任，心理卫生中心主任

现任职称:

主任医师，博士生导师，研究员。

科研成果:

自1991年以来，作为项目主要负责人或主要执行人共参加国家自然科学基金资助课题10项，国家教委博士点基金资助课题4项，CMB资助课题2项，卫生部杰出人材基金资助课题1项，973课题1项。2002年获国家自然科学基金委杰出青年基金课题资。目前已在国内外杂志上发表论文80多篇，其中SCI引用的论文50多篇。参编专业参考书章节四篇。

发表论文情况

一、在国际学术期刊上发表的论文

1. L Yang, Tao Li, C Wiese, L Lannfelt, P Sokoloff, CT Xu, Z Zeng, JC Schwartz, XH Liu, HW Moises, No Association between schizophrenia and homozygosity at the D3 dopamine receptor gene. Am J Med Genetic (Neuropsychiatric Genetics) 1993; 48:83

2. Tao Li, L Yang, C Wiese, CT Xu, Z Zeng, B Giros, MG Caron, HW Moises, XH Liu, No association between alleles or genotypes at the dopamine transporter gene and schizophrenia. Psychiatry Research 1994; 52:17

3. Hans W Moises, Liu Yang, Tao Li, Bent Havsteen, Rolf Fimmers, Max P. Baur, Xiehe Liu, Irving I Gottesman, Potential linkage disequilibrium between schizophrenia and locus D22S278 on the long arm of chromosome 22. Am J Med Genetic (Neuro-psychiatric Genetics) 1995; 60:465

4. Chromosome 22 Collaborative Linkage Group, A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12. American Journal of Medical Genetics (Neuropsychiatric Genetics), 1996: 67:40-45.

5. Tao Li, H Vallada, R Bell, X Liu, T Xie, DA Collier, CNTF and psychiatric disorders. Nature Genetics, [Correspondence] 1996; 13:143.

6. DA Collier, MJ Arranz, P Sham, S Battersby, P Gill, KJ Aitchison, M Sodhi, Tao Li, B Smith, J Morton, RM Murry, D Smith, G Kirov (1996) The serotonin transporter is a potential susceptibility gene for bipolar affective disorder. Neuroreport, 1996; 7:1675.

7. Tao Li, PC Sham, HP Vallada, T Xie, X Tang, X Liu, DA Collier, (1996) Preferential transmission of the high activity allele of COMT in schizophrenia. Psychiatric Genetics, 1996; 6:131

8. DA Collier, G Stober, T Li, A Heils, M Catalano, D Di Bella, MJ Arranz, RM Murray, HP Vallada, D Bengel, CR Muller, GW Roberts, E Smeraldi, G Kirov, P Sham and KP Lesch, A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders. Molecular Psychiatry; 1996; 1: 453-460

9. Tao Li, Clive Holmer, Pak Sham, Joe Birkett, George Kirov, K Peter Lesch, John Powell, Simon Lovestone, David Collier, Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset disease. Neuroreport 1997; 8(3): 683-686

10. Tao Li, Homero Vallade, Davis Curtis, Maria Arranzc, Ke Xu, Guiqing Cai, Hong Deng, Jun Liu Robin Murray, Xiehe Liu and David Collier. Catechol-O-methyltransferase Val158Met polymorphism: frequency analysis in Han Chinese subjects and allelic association of the low activity allele with bipolar affective disorder. Phamacogenetics 1997; 7: 349-353

11. Tao Li, Ke Xu, Hong Deng, Guiqing Cai, Jun Liu, Xiehe Liu, Rongan Wang, Xiaoyong Xiang, Jinghua Zhao, Robin M Murray, Pak C Sham and David A Collier. Association analysis of the dopamine D4 gene exon III VNTR and heroin abuse in Chinese subjects. Molecular Psychiatry 1997; 2:413-416

12. David A Collier, Maria J Arranz, Tao Li, Dennis Mupita, Nigel Brown, Janet Treasure. Association between 5-HT2a gene promoter polymorphism and anorexia nervosa. Lancet 1997; 350:412.

13. Tao Li, Xiehe Liu, Ying Hu and Fuming Sheng. Segregation analysis on bipolar affective disorder. Arch of Shanghai Psychiatry 1997; (New)9: 1-2 (in Chinese)

14. H Kunugi, HP Vallada, PC Sham, F Hoda, MJ Arranz, T Li, S Nanko, RM Murray, P McGuffin, M Owen, M Gill, DA Collier. Catechol-O-methyltransferase polymorphisms and schizophrenia: a transmission disequilibrium study in multiply affected families. Psychiatric Genetics 1997; 7(3): 97-101

15. Tao Li, Homero P Vallada, Xiehe Liu, Tao Xie, Xiangdong Tang, Jinghua Zhao, Michael C O Donovan, Robin m Murray, Pak C Sham and David A Collier. Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method. Biological Psychiatry 1998; 44(11): 1160-1165

16. Treasure, J., Collier, D A., Arranz, M J., Li, T., and Mupita, D., Selective serotonin reputake inhibitors in anorexia nervosa. Lancet 1998; 350: 1033-1034.

17. Tao Li, Maria J Arranz, Katherino J Aitchison, Catherine Bryant, Xiehe Liu, Robert W Kerwin, Robin M Murray, Pak Sham, David A Collier. Case-control, haplotype relative risk and transmission disequilibrium analysis of a dopamine D2 receptor functional promoter polymorphism in schizophrenia. Schizophrenia Research 1998; 32: 87-92

18. Li, T., Hu, X., Chandy, G.K., Fantion, E., Kalman, K., Gutman, G., Gargus, J.J., Freeman, B.F., Murray, R.M., Dawson, E., Liu, X., Bruinvels, A.T., Sham, P.C., and Collier, D.A., Transmission disequilibrium analysis of a triplet repeat within the hkCa3 gene using family trios with schizophrenia. Biochemical and Biophysical Research Communications. 1998; 251: 662-665

19. Maria J. Arranz, Tao Li, J. Munro, X. Liu, Robin Murray, David A Collier and R.W. Kerwin, Lack of association between a polymorphism in the promoter region of the dopamine–2 receptor gene and clozapine response. Pharmacogenetics 1998, 8: 481-484

20. He_L, Li_T, Melville_C, Liu_S, Feng_GY, Gu_NF, Fox_H, Shaw_D, Breen_G, Liu_XH, Sham_P, Brown_J, Collier_D, StClair_D. 102T/C polymorphism of serotonin receptor type 2A gene is not associated with schizophrenia in either Chinese or British Populations. American Journal of Medical Genetics, 1999, 88(1): 95-98

21. Gerome Breen, John Brown, David Collier, Sophia Maud, Helen Fox, Tao Li, Duncan Shaw and David St. Clair. The -141C Del/Ins polymorphism of the dopamine receptor 2 gene is associated with schizophrenia in a British population. Am J Med Genetics 1999; 88(4): 407-410

22. Sharon Marsh, Elaina S.R. Collie-Duguid, Tao Li, Xiehe Liu, and Howard L. Mcleod. Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations. Genomics 1999; 58: 310-312

23. Tao Li, Xiehe Liu, Pak C Sham, Katherine J Aitchison, Guiqing Cai, Maria J Arrianz, Hong Deng, Jun Liu, George Kirov, Robin M Murray, David A Collier. Association analysis between dopamine receptor genes and bipolar affective disorder. Psychiatry Research 1999; 86: 193-201

24. G Green, P Sham, T Li, D Shaw, D A Collier and D St Clair. Accuracy and sensitivity of DNA pooling with microsatellite repeats using capillary electrophoresis. Molecular and Cellular Probes 1999; 13: 359-365

25. T Li, G. Breen, J. Brown, R. M. Murray, D.J. Shaw, P.C. Sham, D. St Clair and D.A. Collier. No evidence of linkage disequilibrium between a CAG repeat in the SCA1 gene and schizophrenia in Caucasian and Chinese schizophrenia subjects. Psychiatric Genetics 1999; 9(3): 123-127

26. Collie-Duguid ESR, Pritchard S C, Poerie R H, Sludden J, Collier D A, Li T, McLeod H L. The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian population. Pharmacogenetics 1999; 9(1): 37-42

27. A.J. Makoff, J.M. Graham, M.J. Arranz, J. Forsyth, T.Li, K.J. Aitchison, S.Shaikh and R. A. Grunewald. Association study of dopamine receptor gene polymoprhisms with drug-induced hallucinations in patients with idiopathic Parkinson’s disease. Pharmacogenetics 2000; 10: 43-48

28. Tao Li, Xiehe Liu, Zuo-Hong Zhu, Jinghua Zhao, Xun Hu, David M Ball, Pak C Sham and David A Collier. No association between (AAT)n repeats in the cannabinoid receptor gene (CNR1) and heroin abuse in a Chinese population. Molecular Psychiatry 2000; 5(2): 128-130

29. Tao Li, David Ball, Jinghua Zhao, Robin M Murray, Xiehe Liu, Pak C Sham, and David A Collier. Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11. Molecular Psychiatry 2000; 5: 77-84

30. Tao Li, Xiehe Liu, Zhu Zuo Hong, Jing Hua Zhao, Xun Hu, Pak C Sham and David A Collier. Association analysis of polymorphisms in the mu opioid gene and heroin abuse in the Chinese subjects. Addiction Biology 2000; 5: 181-186

31. Tao Li, Zuo-Hong Zhu, Xiehe Liu, jinghua Zhao, Pak C Sham and David A Collier. Association analysis of polymorphisms in the DRD4 gene and heroin abuse in the Chinese subjects. Am J Med Genetics 2000; 96:616-621

32. Li, T, Underhill, J, Liu XH, Sham PC, Donaldson, P, Murray RM, Wright, P and Collier DA. Transmission disequilibrium analysis of HLA class ii DRB1, DQA1, DQB1 and DPB1 POLYMORPHISMS IN schizophrenia using FAMILY trios FROM a HAN Chinese population. Schizophrenia Research 2001; 49(1-2): 73-78

33. Guiqing Cai, Tao Li, Hong Deng, Jinghua Zhao, Xun Hu, Robin Murray, Xiehe Liu, Pak Sham and David Collier. Affected sibling pair linkage analysis of qualitative and quantitative traits for schizophrenia on chromosome 22 in a Chinese population. Am J Med Genetics. 2001; 105 (4): 321-327

34. Margaret-Mary Ameyaw , Fernando Regateiro, Tao Li, Xiehe Liu , Mohammed Tariq, Abeer Mobarek, Nadia Thornton, Gbolahan O. Folayan, Jessie Githang'a , Anne Indalo, David Ofori-Adjei, David A. Price-Evans and Howard L. McLeod MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity. Pharmacogenetics 2001, 11:217-221

35. Ralf M. Frieboes , Hans W. Moises, Wagner F. Gattaz , Liu Yang, Tao Li, Xiehe Liu, Peter Vetter, Fabio Macciardi, Hai G. Hwu, Fritz Henn. Lack of association between schizophrenia and the phospholipase-A2 genes cPLA2 and sPLA2. American Journal of Medical Genetics (Neuropsychiatric Genetics) 2001, 105(3): 246-249

36. Tao Li, Xiehe Liu, Jinghua Zhao, Xun Hu, David M Ball, El-Wui Loh, Pak C Sham and David A Collier. Allelic association analysis of the 2 receptors, and the serotonin transporterdopamine D2, D3, 5-HT2a and GABA genes with heroin abuse in Chinese subjects. American Journal of Medical Genetics (Neuropsychiatric Genetics) 2002,114: 329-335.

37. Peng R, Gou Y, Yuan Q, Li T, Latsoudis H, Yuan G, Luo D, Liu X, Collier DA. Mutation screening and association analysis of the parkin gene in Parkinson's disease patients from South-west china. Eur Neurol. 2003;49(2):85-9.

38. Shi J, Zhang S, Ma C, Liu X, Li T, Tang M, Han H, Guo Y, Zhao J, Zheng K, Kong X, Zhang K, Su Z, Zhao Z. Association between apolipoprotein CI HpaI polymorphism and sporadic Alzheimer’s disease in Chinese. Acta Neurol Scand, 2004, 109 (2): 140-145.

39. Shi J, Zhang S, Tang M, Liu X, Li T, Han H, Wang Y, Guo Y, Zhao J, Li H, Ma C. Possible association between Cys311Ser polymorphism of paraoxonase 2 gene and late-onset Alzheimer’s disease in Chinese. Brain Res Mol Brain Res, 2004, 120 (2): 201-204.

40. Shi J, Zhang S, Tang M, Liu X, Li T, Wang Y, Han H, Guo Y, Hao Y, Zheng K, Kong X, Su Z, Tong Y, Ma C. The 1239G/C polymorphism in exon 5 of BACE1 gene may be associated with sporadic Alzheimer’s disease in Chinese Hans. Am J Med Genet, 2004, 124B: 54-57.

41. Yi Huang, Tao Li, Yun Wang, Jawaid Ansar, Guo Lanting, Xiehe Liu, Jing Hua Zhao, Xun Hu, Pak C Sham and David Collier. Linkage disequilibrium analysis of polymorphisms in the gene for Myelin Oligodendrocyte Glycoprotein in Tourette Syndrome patients from a Chinese Sample. American Journal of Medical Genetics (Neuropsychiatric Genetics). 2004, 124(1):76-80

42. Tao Li, Chiken Chen, Xun Hu, David Ball, Shih-Ku Lin, Wai Chen1, Pak C Sham, El-Wui Loh, Robin M. Murray, David A Collier. Association study between DRD4 and COMT genes and Methamphetamine Abuse in a Chinese Population. American Journal of Medical Genetics (Neuropsychiatric Genetics). 2004, 129B(1):120-4

43. Tao Li, Xiaohong Ma, Pak Sham, Xueli Sun, Xun Hu, Qiang Wang, Huaqing Meng, Wei Deng, Xiehe Liu, Robin Murray and David A Collier. Evidence for association between novel polymorphisms in the PRODH gene and schizophrenia in a Chinese population. American Journal of Medical Genetics (Neuropsychiatric Genetics). 2004 129B(1):13-5

44. T Li, H Stefansson, E Gudfinnsson, G Cai, X Liu, RM Murray, V Steinthorsdottir, D Januel, VG Gudnadottir, H Petursson, A Ingason, JR Gulcher, K Stefansson and DA Collier. Identification of a novel neuregulin 1 at-risk haplotype in Han schizophrenia Chinese patients, but no association with the Icelandic/Scottish risk haplotype. Molecular Psychiatry. 2004, 9(7): 698-704

45. Yu L, Li T, Robertson Z, Dean J, Gu NF, Feng GY, Yates P, Sinclair M, Crombie C, Collier DA, Walker N, He L, St Clair D. No association between polymorphisms of methylenetetrahydrofolate reductase gene and schizophrenia in both Chinese and Scottish populations. Mol Psychiatry. 2004; 9:1063-5

46. Raymond C.K. Chan, Ronald Y.L. Chen, Eric Y.H. Chen, Tomy C.K. Hui, Eric F.C. Cheung, H.K. Cheung, Pak Sham, Tao Li, and David Collier. The differential clinical and neurocognitive profiles of COMT SNP rs165599 genotypes in schizophrenia. Journal of the International Neuropsychological Society. 2005; 11: 1–3.

47. Tao Li, Feng Zhang, Xiehe Liu, Xueli Sun, Pak C Sham, Caroline Crombie, Xiaohong Ma, Qiang Wang Huaqing Meng, Wei Deng, Phil Yates, Xun Hu, Nicholas Walker, Robin M Murray, David A Collier and David St Clair. Identifying potential risk haplotypes for schizophrenia at DTNBP1 locus in Han Chinese and Scottish populations. Molecular Psychiatry. 2005;10: 1037-1044

48. Zhang F, St Clair D, Liu X, Sun X, Sham PC, Crombie C, Ma X, Wang Q, Meng H, Deng W, Yates P, Hu X, Walker N, Murray RM, Collier DA, Li T. Association analysis of the RGS4 gene in Han Chinese and Scottish populations with schizophrenia. Genes Brain Behav. 2005; 4(7):444-8.

49. Michael E. Talkowski, Howard Seltman, Anne S. Bassett, Linda M. Brzustowicz, Xiangning Chen, Kodavali V. Chowdari, David A. Collier, Quirino Cordeiro, Aiden P. Corvin, Smita N. Deshpande, Michael F. Egan, Michael Gill, Kenneth S. Kendler5, George Kirov, Leonard L. Heston, Pat Levitt, David A. Lewis, Tao Li, Karoly Mirnics, Derek W. Morris, Nadine Norton, Michael C. O’Donovan, Michael J. Owen, Christian Richard, Prachi Semwal, Janet L. Sobell1, David St Clair1, Richard E. Straub, Thelma B.K., Homero Vallada, Daniel R. Weinberger, Nigel M. Williams, Joel Wood, Feng Zhang, Bernie Devlin, and Vishwajit L. Nimgaonkar. Evaluation of a susceptibility gene for schizophrenia: genotype based metaanalysis of RGS4 polymorphisms from thirteen independent samples. Biological Psychiatry. 2006 Accepted for publication.

50. Prata DP, Breen G, Munro J, Sinclair M, Osborne S, Li T, Kerwin R, St Clair D, Collier DA. Bipolar 1 disorder is not associated with the RGS4, PRODH, COMT and GRK3 genes. Psychiatr Genet. 2006 Dec;16(6):229-30.

51. Breen G, Prata D, Osborne S, Munro J, Sinclair M, Li T, Staddon S, Dempster D, Sainz R, Arroyo B, Kerwin RW, St Clair D, Collier D. Association of the dysbindin gene with bipolar affective disorder. Am J Psychiatry. 2006 Sep;163(9):1636-8.

52. Xiaohong Ma, Qiang Wang, Pak C Sham, Xiehe Liu, Sophia Rabe-Hesketh, Xueli Sun, Junmei Hu, Huaqing Meng, Wai Chen, Eric YH Chen, Wei Deng, Raymond CK Chan, Robin M Murray, David A Collier and Tao Li. Neurocognitive deficits in first-episode schizophrenic patients and their first-degree relatives. American Journal of Medical Genetics (Neuropsychiatric Genetics). 2006 Accepted for publication.

53. Qiang Wang, Raymond Chan, Jinhua Sun, Jing Yao, Wei Deng, Xueli Sun, Xiehe Liu, Pak C Sham, Xiaohong Ma, Huaqing Meng, Robin M Murray, David A Collier and Tao Li. Reaction time of the Continuous Performance Test is an endophenotypic marker for schizophrenia: A study of first-episode neuroleptic-naïve schizophrenia, their non-psychotic first-degree relatives and healthy population controls. Schizophrenia Research 2006 (in Press)

二、在国内学术期刊上发表的论文

1. 李涛, 刘协和, 胡应, 沈福民: 双相情感性障碍的分离分析 上海精神医学 1997; 9(1):1-2

2. 李涛, 刘协和, 胡 应: 多巴胺转运体基因与双相情感障碍 中华医学遗传学杂志 1996;13(5):273-277

3. 李涛, 刘协和: 双相情感障碍家系调查报告 中华精神科杂志 1996; 29(3):140/143

4. 李涛, 刘协和, 胡 应等: 遗传和教育抚养因素在双相情感障碍发病中的作用 上海精神医学 1995; 新 7(3):176-178

5. 张岚，刘协和，李涛，等。强迫症药物疗效与六个功能基因的分子药理遗传学研究。中华医学遗传学杂志。2004年，21(5)：479-481

6. 张岚，刘协和，李涛，等。不同发病年龄强迫症患者6种功能基因的分子遗传学研究。中华精神科杂志。2004年，37(4)：198-201

7. 王强，孙学礼，李涛，等。首发精神分裂症患者及其亲属的P300与儿茶酚氧位甲基转移酶基因的相关性研究，中华精神科杂志，2004;37(2):123。

8. 马小红，王强，孙学礼，李涛等，首发精神分裂症神经认知功能的遗传学分析。中华精神科杂志，2004;37(3)：140-144。

9. 马小红，王英成，王强，李涛等，首发精神分裂症临床表现与22号染色体上可能候选基因的关联分析。中华精神科杂志，2004;37(3)：145-148。

10. 马小红、王英成、李涛、黄 颐、刘协和、吴 斌、师建国：不同年龄双相情感性精神障碍患者与多巴胺D2、儿茶酚氧位甲基转移酶基因多态性的关联分析 中华精神科杂志 2003;36(1):21-24

11. 马小红、周 琴、李涛、王英成、黄 颐、孙学礼、刘协和、师建国、吴 斌：双相情感障碍与DRD3、DRD2和COMT基因多态性的关联分析. 中国神经精神疾病杂志. 2003;29(2):84-87

12. 曹莉萍、李涛、刘协和：海洛因依赖与多巴胺D2受体基因的关联分析 中华精神科杂志 2003; 36(1):31-33

13. 曹莉萍、李涛、刘协和：海洛因依赖与儿茶酚胺氧位甲基转移酶基因的关联研究中华医学遗传学杂志 2003;20(2):127-130

14. 黄 颐、刘协和、许 珂、李晓帆、李涛：精神分裂症患者细胞色素P450 2D6酶基因多态性与利培酮治疗效应的关系 中华精神科杂志 2002;35(2):103-106

15. 曹莉萍、李涛、刘协和：海洛因依赖与多巴胺D4受体基因的关联分析 中国神经精神疾病杂志 2002; 28(1):60

16. 黄 颐、刘协和、李涛等：多巴胺D4受体第3外显子48bp 可变重复序列多态性与抽动障碍的传递不平衡检测 中华医学遗传学杂志 2001;19(2)：100-103

17. 蔡贵庆、伍新尧、李涛、David A. Collier、刘协和、冯炳建、邓红、童大跃、 李建金、区敬华：家族性精神分裂症的定量性状与1号染色体的连锁分析 中华医学遗传学杂志 2002;19(4):281-284

18. 蔡贵庆、伍新尧、李涛、David A. Collier、刘协和、冯炳建、邓 红、童大跃、李建金、区敬华：中国人群中家族性精神分裂症与1号染色体的连锁分析 中华医学遗传学杂志 2002; 19(6):491-494

19. 曹莉萍、李涛、许 珂、刘协和：海洛因依赖与儿茶酚胺氧位甲基转移酶基因-287 A/G 多态性的关联研究 中华医学遗传学杂志 2002; 19(6):499-501

20. 彭 蓉、苟婴如、袁 强、李涛、袁光固、罗德儒、刘协和、David A. Collier: 多巴胺D2受体基因启动子多态性与帕金森病的关联研究 中华医学遗传学杂志 2002; 19(6):524-525

21. 黄 颐、刘协和、李涛等：5-HT 102T/C 多态性与Tourette综合征的病例对照及核心家系关联分析 中华医学遗传学杂志 2001; 18(1):11-13

22. 曹莉萍、李涛、许珂、刘协和：自杀未遂与5-羟色胺2A受体基因的关联分析. 中华医学遗传学杂志 2001;18(3):195-197

23. 蔡贵庆、邓红、李涛、刘协和：精神分裂症受累同胞临床特征的研究 临床精神医学杂志 2001;11(4):232-235

24. 蔡贵庆、李涛、邓 红、吴梅筠、刘协和、David A. Collier: 中国人群中精神分裂症与22号染色体的连锁不平衡研究 中华医学遗传学杂志 2001;18(5):335-337

25. 曹莉萍、李涛、许珂、刘协和：自杀未遂与5-羟色胺2A受体基因的关联分析. 中华医学遗传学杂志 2001;18(3):195-197

26. 蔡贵庆、邓红、李涛、刘协和：精神分裂症受累同胞临床特征的研究 临床精神医学杂志 2001;11(4):232/235

27. 唐牟尼，李涛，刘协和，韩海英，唐铭民，Collier DA: 载脂蛋白E、5-羟色胺转运体基因多态性与阿尔茨海默病的关联分析 中华精神科杂志 2000;33(3)：145-148

三.参编章节

1. 李 涛，精神疾病的遗传。杨徳森主编： 精神病学基础。湖南科技出版社1994

2. 李 涛，情感障碍的遗传研究。姚芳传主编：情感性精神障碍。湖南科技出版社1998

3. 赵京华，李涛，Pak Chung Sham。连锁分析和关联分析。贺林主编：解码生命：人类基因组计划和后基因组计划。科学出版社2000

4. David A Collier, Tao Li. Genetic epidemiology 2: Molecular Genetics. IN: Prince et al. ed. Practical Psychiatric Epidemiology. Oxford University Press. 2003